Transnitrosylation of XIAP Regulates Caspase-Dependent Neuronal Cell Death
نویسندگان
چکیده
منابع مشابه
Contribution of p53-dependent caspase activation to neuronal cell death declines with neuronal maturation.
Caspases play a pivotal role in neuronal cell death during development and after trophic factor withdrawal. However, the mechanisms regulating caspase activity and the role played by caspase activation in response to neuronal injury is poorly understood. The tumor suppressor gene p53 has been implicated in the loss of neuronal viability caused by excitotoxic and DNA damaging agents. In the pres...
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ژورنال
عنوان ژورنال: Molecular Cell
سال: 2010
ISSN: 1097-2765
DOI: 10.1016/j.molcel.2010.07.002